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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of retinoblastoma (RB)
ncRNA name hsa-miR-513a-5p
ncRNA Category miRNA
Disease name retinoblastoma (RB)
Species Homo sapiens
Tissues/Cell_line RB cell line Y79
Methods RT-PCR, qPCR, flow cytometry, transfection, luciferase reporter assay
Expression pattern down-regulated
Functional description Etoposide can promote B7-H1 expression in Rb cells, which may be associated with chemoresistance. miR-513a-5p inhibits the mRNA and protein expression of B7-H1 via binding to the 3'-UTR of B7-H1 mRNA.
PubMed ID 22886978
Year 2012
Title Effect of miR-513a-5p on etoposide-stimulating B7-H1 expression in retinoblastoma cells.
Drug-related ncRNA YES (Etoposide)

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